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Appetite and body weight [electronic resource]
להגדלת הטקסט להקטנת הטקסט- ספר
There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single f
| כותר |
Appetite and body weight [electronic resource] : integrative systems and the development of anti-obesity drugs / edited by Tim C. Kirkham and Steven J. Cooper. |
|---|---|
| מהדורה |
1st ed. |
| מוציא לאור |
Amsterdam Boston : Elsevier Academic Press |
| שנה |
c2007 |
| הערות |
Description based upon print version of record. Includes bibliographical references and index. English |
| הערת תוכן ותקציר |
Front cover APPETITE AND BODY WEIGHT Copyright page Table of Contents Contributors CHAPTER 1: Introduction and Overview CHAPTER 2: Cortical Systems Involved in Appetite and Food Consumption I. INTRODUCTION II. FOOD MOTIVATION III. CORTICAL REPRESENTATIONS OF SENSORY INPUTS IV. CONCLUSION Acknowledgments References CHAPTER 3: The Nucleus Accumbens Shell as a Model of Integrative Subcortical Forebrain Systems Regulating Food Intake II. THE REGULATION OF FEEDING BEHAVIOR BY THE NUCLEUS ACCUMBENS SHELL III. AFFERENT PROJECTIONS TO THE AcbSh THAT MAY BE INVOLVED IN REGULATING FOOD INTAKEIV. DOWNSTREAM COMPONENTS OF THE FUNCTIONAL AcbSh FEEDING CIRCUIT V. THE AcbSh FEEDING CIRCUIT AS A POTENTIAL SITE FOR PATHOLOGY AND THERAPEUTIC INTERVENTION IN THE TREATMENT OF EATING DISORDERS CHAPTER 4: Hypothalamic Neuropeptides and Feeding Regulation II. NEUROPEPTIDE Y III. THE OREXINS IV. MELANIN-CONCENTRATING HORMONE V. CONCLUSION CHAPTER 5: Brainstem-Hypothalamic Neuropeptides and the Regulation of Feeding I. THE CONTROL OF FEEDING II. NEURAL INTEGRATION BY THE DORSAL VAGAL COMPLEXIII. CONSIDERATIONS IN ASSESSING THE ROLE OF "NEUROPEPTIDES" IV. "HUMORAL" INTERACTIONS WITH THE DORSAL VAGAL COMPLEX V. INTRINSIC PEPTIDERGIC NEURONS OF THE DORSAL VAGAL COMPLEX VI. DESCENDING PEPTIDERGIC REGULATION OF BRAINSTEM FEEDING CIRCUITS VII. SUMMARY AND POTENTIAL FOR DRUG DEVELOPMENT CHAPTER 6: The Gut-Brain Axis in the Control of Eating II. GASTRIC MECHANORECEPTION III. INTESTINAL CHOLECYSTOKININ (CCK) IV. AMYLIN V. GHRELIN VI. POTENTIALS AND PROBLEMS OF GUT-BRAIN AXIS SIGNALS IN THE TREATMENT OF OBESITYReferences CHAPTER 7: Integration of Peripheral Adiposity Signals and Psychological Controls of Appetite I. INTRODUCTION AND OVERVIEW II. MESOLIMBIC DOPAMINE CIRCUITRY AND ENERGY REGULATORY SIGNALS III. BRAIN OPIOID SYSTEMS AND ENERGY REGULATORY SIGNALS IV. ENDOCANNABINOIDS AND ENERGY REGULATORY SIGNALS V. LHA CIRCUITRY AND ENERGY REGULATORY SIGNALS VI. OTHER CNS SITES: TARGET FOR FUTURE STUDIES? VII. HUMAN AND CLINICAL STUDIES: AT THE FOREFRONT OF OUR KNOWLEDGE VIII. CONCLUDING REMARKS ReferencesCHAPTER 8: Brain Reward Systems for Food Incentives and Hedonics in Normal Appetite and Eating Disorders II. POSSIBLE ROLES OF BRAIN REWARD SYSTEMS IN EATING DISORDERS III. UNDERSTANDING BRAIN REWARD SYSTEMS FOR FOOD "LIKING" AND "WANTING" IV. "WANTING" WITHOUT "LIKING" V. A BRIEF HISTORY OF APPETITE: FOOD INCENTIVES, NOT HUNGER DRIVES VI. CONNECTING BRAIN REWARD AND REGULATORY SYSTEMS VII. CONCLUSION CHAPTER 9: Pharmacology of Food, Taste, and Learned Flavor Preferences II. PHARMACOLOGY OF FOOD PREFERENCE III. PHARMACOLOGY OF UNLEARNED TASTE PREFERENCE AND REACTIVITY |
| היקף החומר |
1 online resource (385 p.) |
| שפה |
אנגלית |
| מספר מערכת |
997010710529105171 |
תצוגת MARC
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