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Principles of fermentation technology

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The successful structure of the previous edition of Principles of Fermentation Technology has been retained in this third edition, which covers the key component parts of a fermentation process including growth kinetics, strain isolation and improvement, inocula development, fermentation media, fermenter design and operation, product recovery, and the environmental impact of processes. This accurate and accessible third edition recognizes the increased importance of animal cell culture, the impact of the post-genomics era on applied science and the huge contribution that heterologous protein production now makes to the success of the pharmaceutical industry. This title is ideally suited for both newcomers to the industry and established workers as it provides essential and fundamental information on fermentation in a methodical, logical fashion. Stanbury, Whitaker and Hall have integrated the biological and engineering aspects of fermentation to make the content accessible to members of both disciplines with a focus on the practical application of theory. This text collates all the fermentation fundamentals into one concise reference, making it a valuable resource for fermentation scientists, as well as those studying in the field.-- Source other than Library of Congress.

Title Principles of fermentation technology / Peter F. Stanbury, Allan Whitaker, Stephen J. Hall.
Edition 3rd ed.
Publisher Amsterdam : Elsevier
Creation Date [2017]
Notes Includes index.
Content Cover
Title Page
Copyright Page
Dedication
Contents
Acknowledgments
Chapter 1 - An introduction to fermentation processes
The range of fermentation processes
Microbial biomass
Microbial enzymes
Microbial metabolites
Recombinant products
Transformation processes
The chronological development of the fermentation industry
The component parts of a fermentation process
References
Chapter 2 - Microbial growth kinetics
Batch culture
Exponential phase
Deceleration and stationary phases
Continuous culture
Multistage systems
Feedback systems
Internal feedback
External feedback
Comparison of batch and continuous culture in industrial processes Biomass productivity
Metabolite productivity
Continuous brewing
Continuous culture and biomass production
Comparison of batch and continuous culture as investigative tools
Fed-batch culture
Variable volume fed-batch culture
Fixed volume fed-batch culture
Fed-batch culture at a constant specific growth rate
Cyclic fed-batch culture
Application of fed-batch culture
Examples of the use of fed-batch culture
Chapter 3 - The isolation and improvement of industrially important microorganisms
Isolation of industrially important microorganisms Isolation methods utilizing selection of the desired characteristic
Enrichment liquid culture
Enrichment cultures using solidified media
Isolation methods not utilizing selection of the desired characteristic-from the "Waksman platform" to the 1990's
Screening methods and high throughput screening
Return of natural products
Broadening the base of the discovery process and maximizing gene expression
Improvement of industrial microorganisms
Improvement of strains producing primary biosynthetic products
Selection of induced mutants synthesizing improved levels of primary metabolites Isolation of Corynebacterium glutamicum and the role of permeability in the glutamate fermentation
Isolation of mutants that do not produce feedback inhibitors or repressors
Isolation of mutants that do not recognize the presence of inhibitors and repressors
The use of recombination systems for the improvement of primary metabolite production
Transduction, transformation, and protoplast fusion
Recombinant DNA technology
Postgenomic era-the influence of genomics, transcriptomics, and fluxomics on the improvement of primary metabolite producers Application of genomics
Application of transcriptomics
Application of metabolic flux analysis and a systems biology approach
Improvement of strains producing secondary biosynthetic products
Isolation of mutants producing improved yields of secondary metabolites
The empirical approach
Use of directed selection in the isolation of improved secondary metabolite producers
Use of recombination systems for the improvement of secondary metabolite production
The application of the parasexual cycle
Extent 1 online resource (826 p.)
Language English
Copyright Date ©2017
National Library system number 997011505172405171
MARC RECORDS

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