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Osteoporosis [electronic resource]
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Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 percent continuing to make osteoporosis a hot topic in medicine. This newest edition covers everything from basic anatomy and physiology to diagnosis,
| Title |
Osteoporosis [electronic resource] / edited by Robert Marcus ... [et al.]. |
|---|---|
| Edition |
3rd ed. |
| Publisher |
Amsterdam Boston : Elsevier/Academic Press |
| Creation Date |
c2008 |
| Notes |
Description based upon print version of record. Includes bibliographical references and index. English |
| Content |
Front Cover Osteoporosis Copyright Page Contents Contributors Preface Part I: Introduction Chapter 1: The Bone Organ System: Form and Function I. Introduction II. Composition and Organization of Bone III. Cellular Components of Bone IV. Bone Homeostasis V. Bone Mechanics VI. Summary References Chapter 2: The Nature of Osteoporosis I. Defining Osteoporosis II. Material and Structural Basis of Skeletal Fragility III. Conclusions Chapter 3: The Economics of Osteoporosis II. Cost of Illness Studies: Characterizing the Magnitude of the Health ProblemIII. Cost-Effectiveness Analyses: Identifying Efficient Osteoporosis Care Strategies IV. Future Research Directions Acknowledgments Chapter 4: Reflections on Osteoporosis II. Definition III. Diagnosis IV. Fragility Fractures V. Bone Density and Fracture Risk VI. Pathogenesis VII. Prevention VIII. Treatment IX. Conclusions Chapter 5: Skeletal Heterogeneity and the Purposes of Bone Remodeling: Implications for the Understanding of Osteoporosis II. Skeletal HeterogeneityIII. The Purposes of Bone Remodeling IV. Implications for Understanding Osteoporosis Part II: Basic Science of Bone Biology Chapter 6: Osteoblast Biology I. Overview II. Embryonic Development of the Osteoblast Phenotype: Lessons for Bone Formation in the Postnatal Skeleton III. Development Sequence of Osteoblast Phenotype Development IV. Phenotype Properties of Osteogenic Lineage Cells V. Molecular Mechanisms Mediating Progression of Osteoblast Growth and Differentiation VI. Conclusion Chapter 7: Osteoclast Biology I. IntroductionII. Key Osteoclast Differentiation Pathways III. The Fully Differentiated Osteoclast: Mechanisms of Bone Degradation IV. Bone Resorption Coordinated by Intermediate Proteins V. Osteoclast Death VI. Mechanistic Approaches to Modification of Osteoclastic Activity In Vivo VII. Regulation of Osteoclastic Differentiation and Activity In Vivo VIII. Interaction of Hormonal and Local Signals with Osteoclast Activity IX. Diseases with Altered Bone Resorption Chapter 8: Osteocytes II. Osteocyte Ontogeny III. Osteoid-Osteocytes IV. Osteocyte Selective Genes/Proteins and their Potential FunctionsV. Morphology of Osteocytes: Lacunocanalicular System and Dendrite Formation VI. Osteocyte Cell Models VII. Mechanisms and Response of Osteocytes to Mechanical Forces VIII. Osteocyte Signals for Bone Formation IX. Osteocyte Signals for Bone Resorption X. Osteocyte Apoptosis XI. Osteocyte Modification of their Microenvironment XII. Osteocyte Density XIII. Role of Gap Junctions and Hemichannels in Osteocyte Communication XIV. Osteocytes in the Embryonic and the Adult Skeleton XV. The Implications of Osteocyte Biology for Bone Disease |
| Extent |
1 online resource (1987 p.) |
| Language |
English |
| National Library system number |
997010715351605171 |
MARC RECORDS
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